Adriaan van den Spiegel (or Spieghel), name sometimes written as Adrianus Spigelius, was a Flemish anatomist born in Brussels. For much of his career he practiced medicine in Padua, and is considered one of the great physicians associated with the city. At Padua he studied anatomy under Girolamo Fabrici.
His best written work on anatomy is De humani corporis fabrica libri X tabulis aere icisis exornati, published posthumously in 1627. In his 1624 treatise De semitertiana libri quatuor, he gave the first comprehensive description of malaria.
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